Preclinical imaging

Preclinical imaging is considered to be a revolutionary technology, can be in the true sense for clinical provides a unique living conversion method, clinical manifestation and treatment for monitoring disease intervention.By using the same technology and disease biomarkers, at the same time speed up decision-making in the preclinical and clinical stage, and enhance confidence in the curative effect.Compared with the traditional experiment in vitro tissue biopsies, preclinical imaging has many advantages, it can not only obtain anatomic information, but also in the same animals measurement function, metabolism, cell and molecular data.In addition, through the longitudinal to experimental animals imaging (i.e., at different time points on a more accurate quantitative determination), can get along with all of the animals in the disease, efficacy, and toxicity effect all aspects of the situation.For any research, the technology can be big scope to reduce the amount of required experimental animals, which makes the animal research can follow the principle of the 3 rs (reduce optimization - alternative), to achieve the best effect.

Brooke to provide the most comprehensive preclinical imaging system, covers the multimodal imaging system, industry leading Skyscan combination (microCT and Si78 combination of PET/CT) as well as the Albira Si PET/SPECT/CT triad system.Multi-mode system such as the cutting edge of BioSpec MRI system, it is equipped with the highest strength magnets on the market and have the highest sensitivity, can also optionally combined with a PET, for at the same time/radioactive ligand successively (Si78) measurements.The research target validation, drug target interaction/lead optimization and molecular biological distribution/receptor, pharmacology and toxicology, all of the above system can play a key role.This means that they apply to all areas of the disease.In addition, due to many aspects of the chronic diseases will continue to the next phase, which can be detected in the process of natural development of disease specific targets.So in the study of chronic disease, their effect is particularly prominent.

Brooke is ahead in the industry research and development of the imaging system, not only provide imaging technology, but also for MRI and multimodal treatment system to provide animal accessories and peripherals, to optimize the workflow.Has the highest sensitivity of MRI including our patented technology - CryoProbe, it can achieve 3-5 times the signal to ascend, and multimodal processing system can be applied to all models.